“
“The nucleotide sequence of

the mitochondrial genome of the solecurtidae Bivalvia mollusca Sinonovacula constricta (GenBank accession number EU880278) has been determined and is reported here. We determined the complete mitochondrial genome sequence using long-PCR ATM/ATR mutation and. Shot Gun Sequencing. Contained within the 17 225 base pairs (bp) are the two ribosomal RNA genes and 12 protein coding genes typical of metazoan mitochondrial genomes. The S. constricta mitochondrial DNA (mtDNA) did not contain a gene for atp8, similar to the mtDNA of Crassostrea virginica, Crassostrea giga and Mytilus edulis. The S. constricta mtDNA is 67.0% A+T (A 25.9%, C 10.5%, G 22.5%, and T 41.1%). This value is higher than that for many invertebrate mitochondrial genomes. Only 19 putative tRNA genes are present in S. constricta and 27 noncoding regions, of which two are large in size. The trnE and trnW genes as well as a second trnS were absent in S. constricta. The gene arrangement of S. constricta is different from the other Bivalvia genomes.”
“Disturbing data reveal the prevalence

of intestinal parasites and their relationship with socio-environmental factors among Mbya-Guarani Indians. The prevalence was determined by spontaneous sedimentation in water, centrifugation-floatation, and Kato-Katz. A socioeconomic questionnaire was submitted to each family. The overall prevalence of intestinal parasites was 88.7%, and 45.5% were polyparasitized. There 3-MA clinical trial was 90.5% prevalence of enteric parasites in children (1-12-year-old), and 85% among 13-65-year-old individuals, indicating that both age groups are extensively parasitized. The parasite load https://www.selleckchem.com/products/mln-4924.html was low to moderate for geohelminths and 75% of the families did not have latrine, thus the practice of defecation occurred outdoors.

These findings suggest that the multiple intestinal parasitism in the Mbya-Guarani community is high to the point of being the rule, and that it relates essentially to the traditional lifestyle and health habits. It is urgently necessary to implement the association of anti-parasitic treatment with sanitation improvement. This should be done simultaneously with health education activities for this population.”
“Background and Aims Most lichens form associations with Trebouxia phycobionts and some of them simultaneously include genetically different algal lineages. In other symbiotic systems involving algae (e. g. reef corals), the relative abundances of different endosymbiotic algal clades may change over time. This process seems to provide a mechanism allowing the organism to respond to environmental stress. A similar mechanism may operate in lichens with more than one algal lineage, likewise protecting them against environmental stresses. Here, the physiological responses to oxidative stress of two distinct Trebouxia phycobionts (provisionally named TR1 and TR9) that coexist within the lichen Ramalina farinacea were analysed.

03). A higher percentage of urologists from the ES recommended low animal protein intake to all stone formers than urologists from the

NCS (69% ES, 47% NCS; P < .05).\n\nCONCLUSIONS Urologists Selleck 3 MA from both the NCS and the ES, despite differences in the type of practice, subspecialty interest in endourology and geographic location of practice, have similar medical and nutritional practices when counseling patients in the prevention of stone disease. UROLOGY 77: 291-294, 2011. (C) 2011 Elsevier Inc.”
“As recent chemotherapy regimens for metastatic colorectal cancer become more and more effective in a neoadjuvant setting before liver surgery, a “complete” clinical response is sometimes documented on imaging. Without operation though, metastatic recurrence is likely to commence within 12 months. Surgeons now face the problem to resect non-visualizable and non-palpable lesions.\n\nComputer-based virtual surgery planning can be used to fuse pre- and postchemotherapy computed tomography data to develop an operative strategy. This information is then intraoperatively transferred to the liver surface using an image-guided stereotactically

navigated ultrasound dissector. This enables the surgeon to perform a resection that is otherwise not possible.\n\nDuring operation, detection of the lesion through palpation selleck chemical or ultrasound was impossible. After registering the virtual operation plan into the navigation system, the planned resection was performed without problems. Histopathologic workup showed vital tumor cells in the specimen.\n\nThe new image-guided stereotactic navigation technique combined with virtual surgery planning can solve the surgeon’s dilemma and yield a successful operation.”
“Aim Observed associations of alcohol with colorectal cancer are prone to distortion by confounding and reverse causation. A Mendelian randomization approach provides an unbiased estimate of the association using the aldehyde dehydrogenase

2 (ALDH2) variant as a surrogate of alcohol exposure.\n\nMethod A meta-analysis was performed to assess the association between the ALDH2 genotype and Selleck LY3023414 colorectal neoplasia, using the ALDH2 genotype as a marker of alcohol intake.\n\nResults The pooled odds ratio (OR) of colorectal neoplasia was 1.31 (95% CI, 1.01-1.70) for the Glu/Glu vs the Lys/Lys genotype. There was no evidence of interstudy heterogeneity (P = 0.12, I(2) = 42.7). The overall risk for Glu/Lys heterozygotes relative to Lys/Lys homozygotes (under a fixed-effects model) was 1.13 (95% CI, 0.86-1.48). There was no evidence of publication bias for Glu/Glu or Glu/Lys analysis.\n\nConclusion The result supports the role of alcohol in colorectal carcinogenesis based on a Mendelian randomization approach.

“
“Much is compound screening assay unknown about humpback whale (Megaptera novaeangliae) song. The behaviour is limited almost exclusively to males, occurs almost exclusively on the calving grounds and is identical within a population, although it changes periodically throughout the season. Much of current thinking associates humpback whale song with

breeding, although it is not clear if it is intended to attract a mate, fend off challengers, or a combination of the two. There is, however, very little information on the internal biology of these large, sea-going mammals, so the majority of hypotheses have not considered much in the way of physiological mechanisms. Nonetheless, we believe that there is enough information available to infer that a seasonal process of neurological development and atrophy similar to that found in other TDO inhibitor animals may be present in humpback whales. We believe this explains why humpback whale song is not produced between breeding seasons and also why it does not vary between seasons, while it does so within a season. It also adds additional weight to the idea that humpback whale song is an honest signal of fitness to a potential mate or competitor.”
“Aims: This study hypothesized that the sleep-wake

cycle is the major determinant factor affecting blood pressure (BP) dipping in rats and that the sympathovagal imbalance during quiet sleep is associated with the degree of BP fall. Methods: Polysomnographic recording was performed by telemetry on freely moving Wistar-Kyoto rats over 24 h. Active waking and quiet AZD9291 sleep stages were scored using electroencephalogram and electromyogram. BP dipping was assessed as the percentage decline in SBP from dark active waking to light quiet sleep. About 38% of the rats were classified as dippers ( bigger than 10% dip) and 62% as nondippers ( smaller than 10% dip). Results: Among the dipper rats, as compared to dark active waking, the R-R interval and high-frequency

power of heart rate variability (a cardiac vagal index) were increased, whereas low-frequency power of blood pressure variability [(BLF), a vascular sympathetic index)] was decreased in light quiet sleep. The sleep-wake cycle rather than the light-dark cycle played the major role in determining BP dipping. The light-dark change in R-R interval, BLF during dark active waking, and baroreflex sensitivity indices during quiet sleep were significantly lower among nondipper rats than among dipper rats. Correlation analysis revealed that BLF during dark active waking as well as high-frequency power of heart rate variability and baroreflex sensitivity indices during light quiet sleep were correlated with the BP dipping percentage. Conclusion: This study confirms that the sleep-wake cycle is more important than the light-dark cycle in determining BP dipping. Moreover, lower baroreflex control and parasympathetic activity during quiet sleep as well as lower sympathetic activity during active waking are associated with reduced BP dipping.

By taking advantage of pH-responsive mesh property, we demonstrated that dextran macromolecules, whose hydrodynamic radius is between the mesh sizes of the normal and expanded pH conditions, could be encapsulated and stored inside selleck compound of the shell. Moreover, our hydrogel particles showed strong adhesion to human cells. Some of them were even engulfed by the cell membrane and drawn into the cell even with no aid of site-specific moieties. From these results, it is expected that the hydrogel hollow microcapsules synthesized in this study could be used for delivery of macromolecules into the cells. (C) 2014 Elsevier Ltd. All rights reserved.”
“BACKGROUND: The whitefly Bemisia

tabaci (Gennadius) is a complex of cryptic species, some of which, namely the Mediterranean selleckchem (MED) and the Middle East-Asia Minor 1 (MEAM1), are highly

invasive and injurious crop pests worldwide and able to displace local genotypes. Invasiveness of B. tabaci may depend on the phenotype of inherited bacterial endosymbionts. Here, the B. tabaci genetic diversity variation that has occurred in recent years in southern Italy was examined. Whitefly was genotyped by restriction fragment length polymorphism analysis of polymerase-chain-reaction-amplified fragments (PCR-RFLP) of the COI gene and molecular identification of endosymbionts. Possible factors leading to the observed genetic diversity were examined. RESULTS: Q1 and Q2 mitochondrial types of MED, the only species found, coexisted TPX-0005 in the field, while MEAM1 disappeared. A large spreading of Q2 (70% of individuals) was observed for the first time in Italy. Q2 showed a significant female-biased sex ratio and largely outnumbered Q1 on solanaceous hosts, in greenhouses and on insecticide-treated plants. Q1, with an even sex ratio, slightly prevailed

on non-solanaceous hosts, especially on wild and untreated plants. Endosymbiont composition was associated with the mitochondrial type. Hamiltonella and Rickettsia were found at near fixation in Q1 and Q2 respectively; Arsenophonus, Cardinium and Wolbachia were found in both types, although at different frequencies. CONCLUSIONS: Q2 invasion seems to have been favoured by the agroecological conditions of southern Italy and by the female-biased sex ratio. Endosymbionts may have a role in Q2 invasiveness, acting as sex-ratio manipulators (e.g. Rickettsia) and possibly by benefiting the host fitness. (C) 2013 Society of Chemical Industry”
“The cornerstone of lung protective ventilation in patients with acute respiratory distress syndrome (ARDS) is a pressure- and volume-limited strategy. Other interventions have also been investigated. Although no method for positive end-expiratory pressure (PEEP) titration has proven most advantageous, experimental and clinical data support the use of higher PEEP in patients with moderate/severe ARDS.

Then the supernatant from the EPO transfected FLSCs could induce the

CD34+ cell differentiated into hematopoietic cell, especially erythrocytes. This would provide an alternative for cell therapy and blood cell transfusion.”
“Objective: Bell’s palsy rarely recurs or arises bilaterally. We describe unique oral motor sequelae that manifest with bilateral facial palsy.\n\nPatients: Two rare patients with alternating find more bilateral Bell’s palsy experienced compromised mouth movement, affecting eating, speaking, and air exchange, and reduced quality of life.\n\nInterventions: Rehabilitation programs.\n\nMain Outcome Measures: Electromyography and electroneuronography.\n\nResults: On electromyography study, little activity of the orbicularis oris muscle was seen in any mouth or eye movement in Case 1. In Case 2, the electromyography activity of the depressor anguli oris and depressor labii inferioris muscles was stronger than that of

the orbicularis oris muscle. The 2 cases demonstrated different patterns of recovery after the same subsequent treatment.\n\nConclusion: Different patterns of reinnervation occur in bilateral Bell’s palsy. Mouth movement disturbances after bilateral Bell’s palsy are most disabling when incomplete reinnervation GSK2126458 in vivo (as suggested by electroneuronography) of the orbicularis oris muscle occurs. Misdirection of regenerating nerve fibers produces lesser levels of oral motor impairment.”
“Objectives/Hypothesis:

The aim of this study was to describe a technique using the fascia lata (FL) component of the anterolateral thigh (ALT) flap to re-create the orbital floor and lateral nasal wall after total maxillectomy.\n\nStudy Design: Retrospective analysis of medical records.\n\nMethods: 5-Fluoracil A total of 22 patients underwent maxillary reconstruction using a composite ALT-FL flap following cancer resection. All patients underwent total maxillectomies via the Weber-Ferguson approach. The ALT flap was harvested with the deep fascia of the thigh with the aim of using it for lining of the orbital floor and lateral nasal cavity. The FL was sutured to the palatine bone inferiorly, nasal bone and zygomatic bone superiorly, and nasopharyngeal mucosa posteriorly to provide an orbital floor and make a neonasal cavity.\n\nResults: There was 100% free flap survival. Speech was normal in eight (36%) patients, near normal in 10 (46%), and intelligible in four (18%). Seventeen (77%) patients gained a good facial appearance, and five (23%) a fair appearance. Sixteen (73%) patients complained of mild nasal crust formation, and the rest (27%) developed moderate crust.\n\nConclusions: Microvascular reconstruction using a composite ALT-FL flap provided a reliable fascial component for orbital floor and nasal surface reconstruction of total maxillectomy defects.

Conclusions: selleck inhibitor Stuffed bread was the likely vehicle of the outbreak. The laboratory testing capacity for serotypes of Salmonella should be strengthened in Vietnam. Food-handler training in basic food safety measures should be

improved. (C) 2014 The Authors. Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/3.0/).”
“Increased phosphoinositide turnover was first identified as an early signal transduction event initiated by cell surface receptors that were linked to calcium signaling. Subsequently, the generation of inositol 1,4,5-trisphosphate by phosphoinositide-specific phospholipase C enzymes selleck chemicals was defined as the major link between inositide turnover and the cytosolic Ca2+ rise in response to external stimulation. However, in the last decades, phosphoinositides have been emerging as major regulatory lipids involved in virtually every membrane-associated signaling process. Phosphoinositides regulate both the activity and the trafficking of almost all ion channels and transporters contributing to the maintenance of the ionic gradients that are essential for the proper functioning of all eukaryotic cells. Here we summarize the various means by which phosphoinositides affect ion channel functions with special emphasis on Ca2+ signaling and outline the principles that govern the highly selleck compartmentalized roles of these regulatory

lipids. Published by Elsevier Ltd.”
“The role of Nrf2 in disease prevention and treatment is well documented; however the specific role of Nrf2 in skeletal muscle is not well described. The current study investigated whether Nrf2 plays a protective role in an STZ-induced model of skeletal muscle atrophy.\n\nModulation of Nrf2 through siRNA resulted in a more robust differentiation of C2C12s, whereas increasing Nrf2 with sulforaphane treatment inhibited differentiation.

Diabetic muscle atrophy was not dramatically influenced by Nrf2 genotype, since no differences were observed in total atrophy (all fiber types combined) between WT+STZ and KO+STZ animals. Nrf2-KO animals however illustrated alterations in muscle size of Fast, Type II myosin expressing fibers. KO+STZ animals show significant alterations in myosin isoform expression in the GAST. Similarly, KO controls mimic both WT+STZ and KO+STZ muscle alterations in mitochondrial subunit expression. PGC-1 alpha, a well-established player in mitochondrial biogenesis and myosin isoform expression, was decreased in KO control, WT+STZ and KO+STZ SQL muscle. Similarly, PGC-1 alpha protein levels are correlated with Nrf2 levels in C2C12s after modulation by Nrf2 siRNA or sulforaphane treatment.\n\nWe provide experimental evidence indicating Nrf2 plays a role in myocyte differentiation and governs molecular alterations in contractile and metabolic properties in an STZ-induced model of muscle atrophy. (C) 2013 Elsevier Inc.

(2) As much as 260 patients with NMIBC had long-term follow-up before RCX to determine the upgrading and upstaging over time. (3) We compared survival in patients with initial T1 G3 bladder cancer (BC) treated with early RCX (n = 175) versus deferred RCX (n = 99) for recurrent T1 G3.\n\n(1) Our understaging rate was 20.2%. (2) Allowing NMIBC to upgrade portents a 19% survival disadvantage. (3) The 10 years cancer-specific find more survival rate was 78.7% in early and 64.5% in deferred RCX.\n\nEarly, as compared to deferred RCX, has a distinct survival advantage for high-risk NMIBC. Patients

should be counselled accordingly.”
“A novel spiro-sesquiterpene, anthracophyllic acid (1), and a new aristolane sesquiterpene, anthracophyllone (2), were isolated from the mushroom Anthracophyllum sp. BCC18695, together with seven known compounds including aurisins A (3), G (4), K (5), nambinones A, C, axinysones A, and B. The relative configuration of 1 and the hitherto unknown absolute stereochemistry of 3 were determined based on X-ray spectroscopic data. Biological activities including antimalarial activity against Plasmodium falciparum K1 strain, antibacterial property

against GSK1210151A concentration Bacillus cereus, and cytotoxicity against MCF-7, KB, NCI-H187, and Vero cells of the isolated compounds were also evaluated (C) 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.”
“One of the obstacles to more frequent and appropriate use of cardiac magnetic resonance (CMR) in Portugal has been the tack of specific codes that accurately describe these examinations as they are currently performed. In this consensus document, recommendations are made for updating and standardizing CMR codes in Portugal. Guidance on which techniques

and codes should be used in the most common clinical scenarios is also provided. (C) 2012 Sociedade Portuguesa de Cardiologia Published by Elsevier Espana, S.L. All rights reserved.”
“The objective of this study is to investigate the results of total knee arthroplasty (TKA) in traumatic osteoarthritis cases with flexion restriction and to describe the technical details of their management. MS-275 datasheet A multicentre series comprising 40 patients with limitation of flexion less than or equal to 90 degrees was selected from 152 cases of post-traumatic knee arthritis with malunion. We hypothesized that the arthroplasty complication rate would be higher than in other etiologies of limitation of flexion and would require specific management strategies.\n\nPatients: In 23 cases, intra-articular malunion was present, in 15 cases extra-articular, and in two cases combined. The mean flexion was 72 +/- 23 degrees, extension was 6 +/- 6 degrees, and total range of motion (ROM) 66 +/- 23 degrees.

All 4 patients with genotype 2 or 3 reached SVR, as compared with 33% of patients with genotype 1 or 4 (P=0.03). A 48-week course of pegylated IFN-alpha(2a)/ribavirin therapy is effective in patients with recurrent HCV infection after LT.”
“The biliary NSC 683864 tract is a very rare site for the occurrence of extrapulmonary small cell carcinoma. A 68-year-old Japanese female was being followed up for autoimmune hepatitis, and was referred to our hospital because segmental intrahepatic bile duct dilation was found on routine imaging studies, suggesting intrahepatic cholangiocarcinoma. She underwent

left lobectomy of the liver and concomitant resection of the caudate lobe. Microscopic examination of the explanted liver showed a primary composite tumor comprising small cell and mucinous carcinomas that originated in the intrahepatic bile duct. Further immunohistochemical studies, including cytokeratin-19 and chromogranin-A staining, showed the

two cellular components of the tumor to have similar characteristics. The amphicrine properties indicated that the tumor had a monoclonal origin but with biphenotypic differentiation, which was responsible for the histogenesis of this tumor.”
“Mixed matrix blends containing polyimide (PI) and polyhedral oligomeric silsesquioxanes (POSS) are studied with atomistic molecular dynamics simulation. To examine the effect of functional P5091 supplier group, two types of DOSS are considered, either octahydrido silsesquioxane (OHS) or octaaminophenyl silsesquioxane (OAPs). The glass transition temperature of the model PI-OAFS blends increases with the incorporation of GAPS, an observation consistent with recent experiments on these systems. Sapanisertib mw A decrease in glass transition temperature is shown for the model PI-OHS blends. Radial

distribution functions for both blends are presented to show how packing between the inorganic (POSS) and organic (PI) species in the mixed matrix varies as a function of POSS loading and POSS functionalization. In addition, we report the mobility of the PI chains and POSS molecules in the material by calculating the mean square displacement. These results provide molecular insight about thermal property enhancements afforded by POSS-based additives. (c) 2009 Elsevier Ltd. All rights reserved.”
“Emergent operation after renal transplantation (RT) has traditionally been associated with substantial morbidity and mortality. We reviewed 2340 adult patients who underwent RT at our tertiary care center and identified 55 patients who required acute care surgical consultation within 1 year of transplantation. Of these, 43 were treated operatively and 12 nonoperatively. Primary diagnoses were intestinal problems in 29 patients (53%), including diverticulitis, ischemia, perforation, obstruction, and bleeding; cholecystitis in 10 (18%); fluid collections in six (11%), appendicitis and hernias in two each (4%); gastritis in one (2%); and no diagnosis in five (9%).

37% of cases. Heterotopic ossification occurred in 6 hips, and infection, which STI571 supplier resolved

with antibiotics, occurred in 1 patient. Conclusion This combined anterior and posterior approach to THA using a lateral incision in patients with severe, spontaneous ankylosis provides very good exposure, protects the abduction unit and results in good to excellent postoperative recovery.”
“An effort was undertaken to investigate a possibility to quantify hemin, protoporphyrin IX (PPIX), and zinc(II) protoporphyrin IX (Zn(II)PPIX) by means of thin-layer chromatography (TLC). All these porphyrins naturally occur in meat and meat products, and they are known for being metabolically interrelated in a not yet fully understood fashion. In view of the results of a current research in meat chemistry, it seems most likely that Zn(II)PPIX is responsible for the red color of Parma ham (a traditional Italian dry ham). This discovery prompted a novel concept that Zn(II)PPIX might replace sodium nitrite and potassium nitrate in the function of the red color-forming pigment, the latter two

compounds traditionally Bucladesine price used for the same purpose in meat industry, yet known for the formation of the carcinogenic N-nitrosamines as well. In this study, a novel analytical system was proposed for the successful baseline separation of hemin, PPIX, and Zn(II)PPIX, and a possibility was tested of quantifying these three porphyrins in Parma ham. To this effect, the calibration curves GSI-IX in vitro were established for the porphyrin standards. Due to the recognized photosensitivity of hemin,

PPIX, and Zn(II)PPIX, extraction of these three compounds from Parma ham and the thin-layer chromatographic procedure were carried out in the darkness, although a complete blackout was not always possible. One problem remained unsolved in this study, namely the selection of a proper (preferably a visible light resistant, hence a nonporphyrin) internal standard (IS) for the performance of the recovery procedure for hemin, PPIX, and Zn(II)PPIX contained in the meat matrix. Finally, it was concluded that the elaborated TLC procedure can successfully be implemented to quantification of hemin and PPIX in Parma ham (and in the other meat products as well).”
“We demonstrated that IKBKE is overexpressed in human gliomas and that the downregulation of IKBKE markedly inhibits the proliferative and invasive abilities of glioma cells, which is consistent with the results reported by several different research groups. Therefore, IKBKE represents a promising therapeutic target for the treatment of glioma. In the present study, we verified that the microRNAs let-7b and let-7i target IKBKE through luciferase assays and found that let-7b/i mimics can knock down IKBKE and upregulate E-cadherin through western blot analysis. Moreover, the expression levels of let-7b/i were significantly lower in glioma cell lines than that in normal brain tissues, as determined by quantitative real-time PCR.

\n\nConclusions. Patients with advanced HF showed a high number of PVCs with attenuated HRT parameters, reflecting increased circulating catecholamine levels and decreased response

of the autonomic nervous system. Patients who underwent HT showed elevated MHRs, a small number of PVCs, and attenuated HRT values, as corresponds to a denervated heart.”
“Time delay to tuberculosis (TB) diagnosis remains a public health concern. In pregnancy, early TB diagnosis is challenging and acquires further significance due to the risk of infection of the newborn as well as others in the maternity setting. We report a delay of 12 weeks in the diagnosis of TB in a pregnant recent immigrant from Ethiopia to Israel. Contact investigation NU7441 clinical trial revealed pulmonary TB in her two daughters aged four and seven years. We discuss the reasons for this delay in diagnosis, how a more timely diagnosis might have been made, and the dilemma of initiating treatment in unconfirmed TB. (C) 2014 Primary Care Respiratory Society UK. All rights reserved.”
“Objective: To test whether applying a continuous risk-adjusted charting method, using an exponentially weighted moving average (EWMA) chart, would have been useful for monitoring outcomes of patients admitted to the intensive care unit at Bundaberg Base Hospital, Queensland, between November 2000 and December 2005.\n\nDesign, setting

and participants: An EWMA chart was constructed to show the change in observed compared with predicted mortality over time, using data submitted to the Australian and New Zealand Intensive Care Society Adult Patient Database. Limitations and practical implications of this monitoring technique check details were evaluated and compared with a routine monitoring technique using the annual standardised mortality ratio.\n\nMain outcome measure: In-hospital mortality.\n\nResults: Data were submitted on three occasions (August 2002, November 2002 and February

2006). In each year before 2005, the EWMA chart showed periods when observed mortality appeared higher than predicted. These periods were not detectable by analysing the data with an annual standardised mortality ratio. selleck Comparison of aggregated data from peer group hospitals suggested that the mortality prediction model (APACHE III-j) was an appropriate risk adjustment model for this analysis.\n\nConclusions: Continuous monitoring of outcomes using an EWMA chart may have advantages over other techniques. Had data been available, analysis with an EWMA chart might have prompted review of processes and outcomes among patients at Bundaberg Base Hospital ICU. Crit Care Resusc 2010; 12: 36-41″
“Objective. To test the hypothesis that transcatheter elimination of left-to-right (L-R) cardiac shunts in former premature infants with bronchopulmonary dysplasia (BPD) is feasible, safe, and is associated with an improvement in respiratory status.\n\nDesign. Retrospective case review.\n\nPatients.