POEM; 2. esophageal tunnel; 3. healing; 4. incision; Presenting Author: EUN KWANG CHOI Additional Authors: SEUNG UK JEONG, SUN-JIN BOO, SOO-YOUNG NA, BYUNG-CHEOL SONG, YOO-KYUNG CHO, HYUN JOO SONG, HEUNG UP KIM Corresponding Author: EUN KWANG CHOI Affiliations: Jeju National University Hospital Objective: Introduction:Saline flushing during the EUS drainage procedure for the peri-rectal abscess is recommended, however, this is time consuming. Furthermore, drainage catheter for irrigation is inconvenient to the patient. We report two cases of peri-rectal abscess which were

treated successfully with high throughput screening compounds only two 7F stents placement without saline flushing or drainage catheter for

irrigation. Selleck Birinapant Methods: Cases description: Results: Case 1. A 48-year-old woman presented with severe low abdominal pain during defecation for a week. She underwent radiation therapy due to cervical cancer 5 months ago. Initial laboratory test showed mild leukocytosis (11,400/μL). CT scan showed 55 mm loculated fluid collection in the peri-rectal space (Fig. 1). The fluid collection was visualized using a curvilinear echoendoscope (GF-UCT240-AL5; Olympus Medical Systems Co., Tokyo, Japan). This was punctured with 19 gauge Echotip® ultra needle (Wilson-Cook Medical Inc., Winston-Salem, NC, USA) through the rectal wall after using Doppler to avoid intervening vessels. One cc of thick pus was aspirated for culture. A 0.035-inch guidewire was passed into the fluid collection. The graded dilation was performed

using a dilating catheter and balloon. One more guidewire was placed using Haber ramp catheter (Wilson-cook Medical, Limerick, Ireland) followed by the placement of two 7F double pigtail plastic stents (Cook Cook Ireland Ltd., Limerick, Ireland). There was no early or delayed selleck inhibitor complication. The procedure was effective in relieving pain within a day. After a week, CT scan showed completely resolved abscess. The stents were retrieved by sigmoidoscopy. Conclusion: Case 2. A 48-year-old man presented with severe abdominal pain and fever for 2 weeks. Initial laboratory test showed leukocytosis (16,600/μL), and mild abnormality of liver function tests. CT scan showed gallbladder empyema. He underwent cholecystectomy. After two weeks of surgery, he complaint low abdominal pain. Follow-up CT scan showed 8 cm loculated fluid collection in the peri-rectal space. He underwent EUS guided drainage procedure following the same methods as above (Fig. 2). Ten cc of brown colored pus was aspirated for culture. After 2 weeks, CT scan showed completely resolved fluid collection. The stents were retrieved by sigmoidoscopy. Key Word(s): 1. Peri-rectal abscess; 2.