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MLW performed the experimental work with assistance from SW. HC assisted with study design and data interpretation. All authors read and approved the final manuscript.”
“Background Biofilms are PRT062607 molecular weight cell-cell or solid surface-attached assemblages of microbes that are entrenched in a hydrated, self-produced matrix [1]. Bacteria growing in biofilms exhibit increased resistance to antimicrobials and host immune response compared to their freeliving, planktonic counterparts due to several reasons like restricted penetration of antimicrobials into a biofilm, decreased growth rate, and expression of possible resistance genes [2]. Klebsiella pneumoniae is an important biofilm forming organism responsible for a wide range of infections placing it among the eight most important nosocomial pathogens [3].

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