Furthermore, homeless persons who use alcohol or drugs may also refuse referrals to hospice and palliative care services due to a range of factors, including real or perceived discrimination in these settings or the preference to die in a familiar environment (e.g., emergency

shelter, hostel, etc.) [30]. Due to these barriers, homeless persons often die with poor health care support [33] and without accessing the end-of-life care Rucaparib system [34]. Song et al. [35] have reported that these barriers may serve as Inhibitors,research,lifescience,medical a selleck inhibitor source of anxiety among homeless persons—namely, that they might have poor access to necessary care (e.g., pain and symptom management) due to financial barriers. Several ways to improve end-of-life care services delivery to homeless populations have been previously identified, and have Inhibitors,research,lifescience,medical included individual-level and environmental recommendations. For example, researchers have recommended that advance care planning be undertaken with homeless persons

and noted that this population is willing to document its end-of-life care preferences [35-39]. Researchers have also documented the benefits of emergency shelter-based end-of-life care services delivery, including cost savings [24] and cultural competence [24,30,40]. And yet, research has not been conducted that has Inhibitors,research,lifescience,medical explored ways to improve the end-of-life Inhibitors,research,lifescience,medical care system as a whole for homeless populations. Research providing systems-level recommendations is urgently needed to identify structural changes that have the potential to increase access and equity in end-of-life care services for homeless populations. This article presents recommendations for improving

the end-of-life care system for homeless persons based on research conducted in six Canadian cities as part of a national study of homelessness and end-of-life care. The main objectives of this study were to identify barriers to end-of-life care services delivery to homeless persons and identify Inhibitors,research,lifescience,medical recommendations to improve the end-of-life care system for this population. The findings presented here take into account the perspectives of health and social services professionals providing care to homeless persons at end-of-life. While this study was carried out in a country with universal health insurance, our findings provide insights that may strengthen end-of-life care services delivery to homeless persons Brefeldin_A elsewhere given the barriers they face to accessing care even when healthcare coverage is available [41]. Methods Study design and participants We conducted qualitative interviews with health and social services professionals in six Canadian cities between February 2007 to August 2008 in which we explored the social and structural factors that impact end-of-life care services delivery to homeless persons.