We hypothesized that choices of pediatric urologists are based on technical factors of the studies themselves, as well as institutional factors unique to their hospital(s). Therefore, we surveyed pediatric urologists to determine their current practices
and preferences of modalities of voiding cystography.
Materials and Methods: We mailed an anonymous survey of 40 questions to all fellows of the American Academy of Pediatrics Section on Urology.
Results: Surveys were returned from 186 of 301 fellows (62%). Of the respondents 57% were in academic, 30% in private and 13% in mixed practices. Given a choice of fluoroscopic voiding cystourethrography, radionuclide cystography and voiding ultrasonography, fluoroscopic voiding cystourethrography was preferred by 98% and 96% of respondents for initial evaluation of urinary tract infection in
males and females, respectively, 96% for assessment of prenatal hydronephrosis, www.selleckchem.com/products/prt062607-p505-15-hcl.html 54% for followup of vesicoureteral reflux, 59% for screening siblings, and 63% and 66%, respectively, after open and endoscopic correction of vesicoureteral reflux. Voiding ultrasonography was preferred by less than 10% of respondents in all groups, and radionuclide cystography was preferred by the remainder. Voiding images of the urethra, child-friendliness of staff, sensitivity and accuracy were factors most important in choosing a test. Of the respondents 83% reported full-time access to pediatric radiologists at their primary hospital, although a minority had full-time access to pediatric radiologists at additional MX69 institutions. Sedation was used in some or most cases by 29%, rarely by 56% and never by 15% of respondents.
Conclusions: Pediatric urologists prefer fluoroscopic voiding cystography in all situations to evaluate vesicoureteral reflux Lonafarnib price but the proportion
varies by indication. Diagnostic and patient issues are of greater concern than radiation dose. Variability in access to pediatric radiologists and ability to obtain the desired study may also alter ordering practices.”
“Purpose: The response of 2-amino-4-([C-14]methylthio)butyric acid ([C-14] Met) uptake and [I-125]3-iodo-alpha-methyl-L-tyrosine ([I-125]IMT) uptake to radiotherapy of C10 glioma cells was compared to elucidate the intracellular reactions that affect the response of 2-amino-4-([C-11] methylthio)butyric acid ([C-11]Met) uptake to radiotherapy.
Methods: After irradiation of cultured (3 Gy) or xenografted C10 glioma cells (25 Gy) using a carbon ion beam, the accumulation of [C-14] Met and [I-125]IMT in the tumors was investigated. The radiometabolites in xenografted tumors after radiotherapy were analyzed by size-exclusion HPLC.
Results: [C-14]Met provided earlier responses to the carbon ion beam irradiation than [I-125]IMT in both Cultured and xenografted tumors.