J Infect Dis 1985,152(5):985–989.PubMedCrossRef 14. Schachter J: Chlamydial infections (first of three parts). N Engl J Med 1978,298(8):428–435.PubMedCrossRef 15. Klint M, Fuxelius H-H, Goldkuhl RR, Skarin H, Rutemark C, Andersson SGE, Persson K, Herrmann B: High-resolution genotyping of Chlamydia trachomatis strains by multilocus sequence analysis. J Clin Microbiol 2007,45(5):1410–1414.PubMedCrossRef 16. Christerson L, Ruettger A, Gravningen K, Ehricht R, Sachse K, Herrmann B: High-resolution genotyping of Chlamydia trachomatis by use of a novel multilocus typing DNA microarray. J Clin Microbiol 2011,49(8):2838–2843.PubMedCrossRef 17. Wang Y, Skilton

RJ, Cutcliffe LT, Andrews E, Clarke IN, Marsh P: Evaluation of a high resolution genotyping method for Chlamydia trachomatis using CH5183284 cell line routine clinical samples. PLoS One 2011,6(2):e16971.PubMedCrossRef 18. Nunes A, Borrego MJ, Gomes JP: Genomic features beyond Chlamydia trachomatis phenotypes: What do we think we know? Infect Genet Evol 2013, 16C:392–400.CrossRef 19. Fehlner-Gardiner C, Roshick C, Carlson JH, Hughes S, Belland RJ, Caldwell HD, McClarty G: Molecular basis defining human Chlamydia trachomatis tissue tropism. A possible role for tryptophan synthase. J Biol Chem 2002,277(30):26893–26903.PubMedCrossRef 20. Caldwell HD, Wood H, Crane

D, Bailey R, Jones RB, Mabey D, Maclean I, Mohammed Z, Peeling R, Roshick C, et al.: Polymorphisms in Chlamydia trachomatis tryptophan synthase genes differentiate between genital and ocular isolates. J Clin Invest 2003,111(11):1757–1769.PubMed selleck 21. Suchland RJ, Rockey DD, Bannantine JP, Stamm WE: Isolates of Chlamydia trachomatis that occupy nonfusogenic inclusions lack IncA, a protein localized to the inclusion membrane. Infect Immun 2000,68(1):360–367.PubMedCrossRef 22. Kuo CC, Grayston T: Interaction

of Chlamydia trachomatis organisms and HeLa 229 cells. Infect Immun 1976,13(4):1103–1109.PubMed 23. Suchland Nintedanib (BIBF 1120) RJ, Rockey DD, Weeks SK, Alzhanov DT, Stamm WE: Development of secondary inclusions in cells infected by Chlamydia trachomatis . Infect Immun 2005,73(7):3954–3962.PubMedCrossRef 24. Srinivasan T, Bruno WJ, Wan R, Yen A, Duong J, Dean D: In vitro recombinants of antibiotic resistant Chlamydia trachomatis strains have statistically more breakpoints than clinical recombinants for the same sequenced loci and exhibit selection at unexpected loci. J Bacteriol 2011,194(3):617–626.PubMedCrossRef 25. Smith GR: Homologous recombination near and far from DNA breaks: alternative roles and contrasting views. Annu Rev Genet 2001, 35:243–274.PubMedCrossRef 26. Baldo L, Bordenstein S, Wernegreen JJ, Werren JH: Widespread recombination throughout Wolbachia MAPK inhibitor genomes. Mol Bio Evol 2006,23(2):437–449.CrossRef 27. Bailey TL, Elkan C: Fitting a mixture model by expectation maximization to discover motifs in biopolymers. Proc Int Conf Intell Syst Mol Biol 1994, 2:28–36.