This paper details the protocol employed for a citizen science evaluation of the Join Us Move, Play (JUMP) program, a comprehensive strategy to boost physical activity amongst children and families aged 5 to 14 in Bradford, UK.
This JUMP program evaluation seeks to comprehend the lived experiences of children and families related to physical activity and participation. A collaborative and contributory citizen science approach underpins this study, including focus groups, parent-child dyad interviews, and participatory research activities. This study and the JUMP program will adapt based on the feedback and data received. We also endeavor to investigate the participant experiences within citizen science, and the appropriateness of a citizen science method for assessing a complete systems approach. Citizen scientists, participating in the collaborative citizen science study, will contribute to the data analysis, utilizing iterative analysis alongside a framework approach.
The University of Bradford has granted ethical approval for study one (E891, focus groups within the control trial, and E982, parent-child dyad interviews), and study two (E992). Through schools or direct communication, participant summaries will accompany the results published in peer-reviewed journals. To establish enhanced dissemination channels, the contributions of citizen scientists will be essential.
Study one, which encompasses E891 focus groups (part of the control trial) and E982 parent-child dyad interviews, and study two (E992), have been approved ethically by the University of Bradford. Results of the study will be presented in peer-reviewed publications, with summaries provided to participants, either through their schools or directly. Citizen scientists' input will be used to develop and expand opportunities for disseminating information.

To comprehensively review empirical evidence on the family's role in end-of-life communication and pinpoint the fundamental communication methods for end-of-life decision-making in family-centered cultural settings.
The communication settings governing the end of line.
This integrative review meticulously followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses reporting protocol. Papers on end-of-life communication with families, published from 1 January 1991 to 31 December 2021, were identified via a search of four databases—PsycINFO, Embase, MEDLINE, and the Ovid nursing database—utilizing the keywords 'end-of-life', 'communication', and 'family'. The data were then extracted and coded into themes to facilitate the analysis process. A quality assessment was performed on all 53 studies that met the eligibility criteria and were identified through the search strategy. The evaluation of quantitative research was conducted using the Quality Assessment Tool, along with the utilization of the Joanna Briggs Institute Critical Appraisal Checklist for qualitative studies.
Family-focused research on end-of-life communication: an evidence-based approach.
Four overarching themes from these studies are: (1) family conflicts surrounding end-of-life communication, (2) the importance of timing end-of-life discussions, (3) the difficulty in designating a single individual to handle end-of-life decisions, and (4) differing cultural perspectives surrounding communication at the end of life.
The review underscored the critical significance of family within end-of-life communication, implying that family involvement is likely to contribute to a better quality of life and a more peaceful death for the patient. A future research agenda should prioritize the development of a family-centric communication model suitable for Chinese and Eastern contexts, focusing on managing family expectations in the disclosure of a prognosis, assisting patients in fulfilling their familial roles, and facilitating effective end-of-life decision-making. Family involvement in end-of-life care should be carefully considered by clinicians, who must tailor their management of family member expectations to reflect the nuances of diverse cultural backgrounds.
This review of current research emphasized the paramount importance of family during end-of-life communication, revealing that family engagement is likely to result in a more positive quality of life and death for patients. To advance the field, future research should cultivate a communication framework attuned to Chinese and Eastern cultural sensibilities. This framework should address family expectations during prognosis disclosure, enabling patients to fulfill their familial obligations during end-of-life decision-making. bioethical issues For effective end-of-life care, clinicians must understand and address the significance of the family's role, customizing their approach to accommodate diverse cultural expectations.

The aim of this study is to delve into patients' accounts of their enhanced recovery after surgery (ERAS) and to identify challenges to the implementation of this program as perceived by patients.
Based on the Joanna Briggs Institute's methodology for conducting synthesis, a systematic review and qualitative analysis were undertaken.
Four databases—Web of Science, PubMed, Ovid Embase, and the Cochrane Library—were systematically examined for pertinent studies. Further investigation included consultation with key authors and their reference materials.
Across 31 studies of the ERAS program, 1069 surgical patients were examined. To set the boundaries of the article search, the inclusion and exclusion criteria were framed with the aid of the Joanna Briggs Institute's advice on Population, Interest, Context, and Study Design. Inclusion criteria encompassed ERAS patients' experiences, qualitative English-language data published between January 1990 and August 2021.
Using Joanna Briggs Institute's standardized data extraction tool for qualitative research, the relevant studies' data were extracted.
Patient priorities within the structure dimension revolved around the punctuality of healthcare responses, the competency of family care providers, and the safety concerns connected to ERAS procedures, which were poorly understood. The process dimension showed that patients needed: (1) thorough and precise information from healthcare providers; (2) effective communication with healthcare providers; (3) individualized treatment plans; and (4) ongoing follow-up care. Laboratory Refrigeration Patients' aspirations, regarding the outcome dimension, centered on the effective relief of severe postoperative symptoms.
From a patient's standpoint, assessing ERAS experiences highlights deficiencies in clinical care practices. This process allows timely intervention in patient recovery issues, thereby reducing obstacles to implementing ERAS effectively.
The CRD42021278631 item needs to be returned.
CRD42021278631: The identification code, CRD42021278631, is presented.

The development of premature frailty is a possibility for individuals with severe mental illness. An intervention to diminish the risk of frailty and the related negative repercussions is crucially needed in this cohort. The study intends to offer new evidence on the usability, acceptance, and initial effectiveness of Comprehensive Geriatric Assessment (CGA) to improve health results in individuals grappling with co-occurring frailty and severe mental illness.
The CGA will be provided to twenty-five participants, experiencing frailty and severe mental illness, between the ages of 18 and 64, recruited from Metro South Addiction and Mental Health Service outpatient clinics. The effectiveness of the embedded CGA in routine healthcare will be measured primarily by its feasibility and acceptability. In addition to other considerations, the variables of frailty status, quality of life, polypharmacy, and diverse mental and physical health aspects are pertinent.
All human subject/patient procedures received ethical clearance from the Metro South Human Research Ethics Committee (HREC/2022/QMS/82272). Disseminating the results of the study will be accomplished via peer-reviewed publications and presentations at professional conferences.
Metro South Human Research Ethics Committee (HREC/2022/QMS/82272) specifically approved procedures conducted on human subjects/patients. The dissemination of study findings will take place within the context of peer-reviewed publications and conference presentations.

The objective of this study was to develop and validate nomograms for anticipating the survival of patients with breast invasive micropapillary carcinoma (IMPC), thus facilitating objective decision-making in the clinical setting.
Utilizing Cox proportional hazards regression analysis, prognostic factors were pinpointed, and these factors were instrumental in building nomograms to predict 3- and 5-year overall survival and breast cancer-specific survival. Sunitinib The nomograms' predictive capacity was examined by applying Kaplan-Meier analysis, calibration curves, the area under the curve (AUC), and calculating the concordance index (C-index). A comparison of nomograms with the American Joint Committee on Cancer (AJCC) staging system was conducted using decision curve analysis (DCA), integrated discrimination improvement (IDI), and net reclassification improvement (NRI).
Patient datasets were derived from the Surveillance, Epidemiology, and End Results (SEER) database. Within this database, cancer incidence information is compiled from 18 U.S. population-based cancer registries.
One thousand three hundred and forty patients were incorporated into the current study following the exclusion of 1893 cases.
The AJCC8 stage's C-index exhibited a lower value compared to the OS nomogram's C-index (0.670 versus 0.766), while the OS nomograms demonstrated superior AUCs compared to the AJCC8 stage (3 years: 0.839 versus 0.735, 5 years: 0.787 versus 0.658). Calibration plots revealed a strong correspondence between predicted and observed outcomes; moreover, DCA analysis indicated that nomograms exhibited superior clinical utility compared to the conventional prognostic method.